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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Senior Showcase 2015
Description
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Oral and poster presentations from Senior Showcase held on April 23, 2015 at Ripon College.
Creator
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Ripon College
Publisher
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Ripon College Lane Library
Date
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April 23, 2015
Contributor
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Scholars Week
Format
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pdf
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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The effect of phenylpropanolamine on the development of the lateral line system, heart rate, and morphology of Danio rerio larvae by Cassie Olson
Subject
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Biology
Description
An account of the resource
Phenylpropanolamine (PPA) is a sympathomimetic drug that is a vasoconstrictor and bronchodilator. In 2000, it was removed from the market due to causing stroke. Research on a relationship between PPA exposure and hair cell development has not yet been observed. The zebrafish (Danio rerio) is a useful model for studying ototoxic effects on hair cells because the lateral line system along the outside of their body is composed of hair cells. Ototoxic effects on the hair cells of the lateral line system can help determine ototoxic effects on the hair cells of the inner ear of mammals and humans. The lateral line system is a mechanosensory organ that senses water flow. When stimulated in zebrafish larvae an escape response is evoked. Using this knowledge, tests were done to stimulate lateral line and determine if there was a difference in the reaction times of larvae which developed in various concentrations of PPA ranging from 0.25 to 1.5 mM until 5 days post fertilization (dpf). Additionally, photos were taken and heart rate was observed after incubation in PPA and after over-night recovery. Reaction time results were determined to be inconclusive. However, heart rate results showed that there was a significant decrease in the heart rate of larvae treated with 0.50 and 0.75 mM PPA until 5dpf. After recovery, larvae treated with 0.25 and 0.50 mM PPA experienced a significant increase in heart rate which was not significantly different from the control. Differences in morphology were observed among concentration groups.
Creator
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Olson, Cassie
Source
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Senior Showcase Poster presentation
Publisher
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Ripon College
Date
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April 23, 2015
Rights
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The author reserves all rights.
Format
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pdf
Identifier
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Major: Biology
Minor: Chemistry
Egg Harbor, Wisconsin
BIO 502.01 - Senior Studies
Biology
cardiovascular system
edema
PPA
recovery
zebrafish